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Tolerogenic nanoparticles inhibit T cell-mediated autoimmunity through SOCS2.

by AnTolRx | Aug 31, 2016 | Publication

Yeste, A. et al. Sci Signal 9, ra61(2016)

IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39.

by AnTolRx | Aug 31, 2016 | Publication

Mascanfroni, I. D. et al. Nat Immunol 14, 1054–1063 (2013).

Nanoparticle-mediated codelivery of myelin antigen and a tolerogenic small molecule suppresses experimental autoimmune encephalomyelitis.

by AnTolRx | Aug 31, 2016 | Publication

Yeste, A., Nadeau, M., Burns, E. J., Weiner, H. L. & Quintana, F. J. Proc Natl Acad Sci USA 109, 11270–11275 (2012).

An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis.

by AnTolRx | Aug 31, 2016 | Publication

Quintana, F. J. et al. Proc Natl Acad Sci USA 107, 20768–20773 (2010).

Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell-like and Foxp3(+) regulatory T cells.

by AnTolRx | Aug 31, 2016 | Publication

Gandhi, R. et al. Nat Immunol 11, 846–853 (2010).
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